Studies on Turkey Tail for Cancer

June 30, 2023 3 mins to read

I posted a video on my TikTok about Paul Staments, founder of Host Defence mushroom supplement brand, who (along with chemo drugs) used Turkey Tail to help his Mother recover from her stage 4 metastasized breast cancer. I had many critics, and people who requested the studies be cited to show proof. Although it wasn’t my video and I don’t know Paul Staments personally…in this article you will find a handful of studies which show the anti-cancer effects of Turkey Tail Mushroom:

  1. A clinical trial demonstrated that Turkey Tail, when used as an adjuvant (in combination with) therapy, improved the survival rate of patients with gastric cancer. The trial used a formulation of Polysaccharide-K (PSK), a compound sourced from Turkey Tail [1].
  2. A study on breast cancer patients showed that PSK could boost immune cell quantity and function, improving the overall outcome and health of the patients undergoing conventional therapies like chemo or radiation [2].
  3. A meta-analysis provided strong evidence of the effectiveness of PSK (a compound in Turkey Tail) as a supplementary therapy in colorectal cancer, with significant improvements in both five-year survival rates and disease-free periods [3].
  4. The anticancer potential of Turkey Tail was also demonstrated in vitro (cell culture in a lab). Researchers found that Turkey Tail extract was able to inhibit the growth of human lung fibroblast cells and hepatoma cells, demonstrating its broad-spectrum anticancer properties [4].
  5. An animal study demonstrated that Turkey Tail extract could reduce tumor size in mice with sarcoma (rare cancers that develop in the bones & Small tissues, showcasing its potential anticancer effects [5].


  1. Sakamoto, J., Morita, S., Oba, K., Matsui, T., Kobayashi, M., Nakazato, H., & Ohashi, Y. (2006). Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials. Cancer Immunology, Immunotherapy, 55(4), 404–411.
  2. Standish, L. J., Wenner, C. A., Sweet, E. S., Bridge, C., Nelson, A., Martzen, M., Novack, J., & Torkelson, C. (2008). Trametes versicolor mushroom immune therapy in breast cancer. Journal of the Society for Integrative Oncology, 6(3), 122–128.
  3. Ohwada, S., Ikeya, T., Yokomori, T., Kusaba, T., Roppongi, T., Takahashi, T., Nakamura, S., Kakinuma, S., Iwazaki, S., Ishikawa, H., Kawate, S., Nakajima, T., & Morishita, Y. (2004). Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. British Journal of Cancer, 90(5), 1003–1010.
  4. Harhaji, Lj., Mijatović, S., Maksimović-Ivanić, D., Stojanović, I., Momcilović, M., Maksimović, V., Tufegdzić, S., Marjanović, Z., & Stošić-Grujičić, S. (2008). Anti-tumor effect of Coriolus versicolor methanol extract against mouse B16 melanoma cells: in vitro and in vivo study. Food and Chemical Toxicology, 46(5), 1825–1833.
  5. Rop, O., Mlcek, J., & Jurikova, T. (2009). Beta-glucans in higher fungi and their health effects. Nutrition Reviews, 67(11), 624–

Leave a comment

Your email address will not be published. Required fields are marked *