Common Nutrient Deficiencies Connected With Statin Medication Use

September 30, 2023 5 mins to read

Statins are a class of medications often used to lower cholesterol levels in the blood and help reduce the risk of cardiovascular disease. But there’s a downside – they can lead to nutritional deficiencies, due to how they operate in the body.

Top 15 List of Common Statins

  1. Atorvastatin (Lipitor)
  2. Simvastatin (Zocor)
  3. Rosuvastatin (Crestor)
  4. Pravastatin (Pravachol)
  5. Lovastatin (Mevacor, Altoprev)
  6. Fluvastatin (Lescol)
  7. Pitavastatin (Livalo, Zypitamag)
  8. Cerivastatin (Removed from the market due to safety concerns)
  9. Simvastatin and Ezetimibe combination (Vytorin) – This is a combination medication where Ezetimibe is not a statin but is used to further reduce cholesterol.
  10. Atorvastatin and Amlodipine combination (Caduet) – Here, Amlodipine is used for blood pressure control and not for cholesterol.
  11. Rosuvastatin and Ezetimibe combination (Liptruzet)
  12. Lovastatin and Niacin combination (Advicor)
  13. Simvastatin and Niacin combination (Simcor)
  14. Atorvastatin and Fenofibrate combination (Caduet) – Fenofibrate is another lipid-lowering agent but not a statin.
  15. Extended-release Fluvastatin (Lescol XL)

List of Nutrient Deficiencies Connected with Statin Use

There are two main deficiencies and then several less common deficiencies. Obviously whether or not someone is deficient can depend on someones dietary intake of these nutrients, as well as their health status and specific biology, But the two top deficiencies connected with statin use, are likely despite dietary intake, unless the individual is on a diet specifically designed to address them.

  1. Coenzyme Q10: Statins block the pathway that makes cholesterol, but CoQ10 is produced in the same route! Low levels can lead to fatigue, muscle weakness, and even heart failure.
  2. Vitamin D: some studies link statins to lower levels, possibly because the body uses cholesterol to make this essential nutrient. Low D can mean weak bones, mood changes, and a weakened immune system.

Less Common Deficiencies

  1. Selenium: Statins may lower levels of selenium, a crucial antioxidant that helps protect the body from oxidative damage. Low selenium levels can impact heart health and over-all immune function.
  2. Omega-3 fatty acids: Statins may reduce the effectiveness of Omega-3 fatty acids, vital for heart health. Omega-3s are also essential for brain health and maintaining a healthy inflammatory response.
  3. Vitamin E: Some research suggests statins can decrease the levels of vitamin E in the blood. Vitamin E, an antioxidant, plays a vital role in maintaining cell health by fighting off harmful free radicals.
  4. Vitamin K: Some studies found statins could interfere with vitamin K production. Vitamin K is important for proper blood clotting and bone health.

Note about Deficiencies

If you’re on statins and haven’t seen a professional, I’d suggest you ask your doctor for blood tests for these nutrients and book an appointment with me so I can put you on a nutritional plan to ensure you are taking the correct amounts either through diet, supplementation, or both. As well as to ensure the most bioavailable form(s) are being taken, that will get your levels up to a healthy amount.

Top 5 Foods Rich in Each Nutrient Listed

  • Coenzyme Q10 (CoQ10): Organ meats, beef, fatty fish (sardines, mackerel), spinach, broccoli
  • Vitamin D: Fatty fish (salmon, mackerel, sardines), fortified dairy products, egg yolk, fortified cereals, cod liver oil
  • Selenium: Brazil nuts, seafood (tuna, halibut, sardines), sunflower seeds, brown rice, chicken
  • Omega-3 Fatty Acids: Chia seeds, flaxseeds, walnuts, fatty fish (salmon, mackerel, sardines), hemp seeds
  • Vitamin E: Almonds, sunflower seeds, spinach, avocado, wheat germ oil
  • Vitamin K: Kale, spinach, broccoli, Brussels sprouts, green leaf lettuce

If you want the specific amounts you should consume in each to make up for deficiencies, book an appointment.

Favorite Supplements for Each Nutrient Listed

Youngevity by Dr. Wallach is one of the few supplement brands I trust, because the vast majority of supplements are owned by Pharmaceutical companies. However Dr. Wallach fought the FDA in court 4 times and won, so he’s about as anti-BigPharma as a Doctor can get. And one of the foremost experts on nutritional deficiencies and related diseases. He also has a few brands under the Youngevity umbrella that are all of the highest quality available.

Again, if you book an appointment I can better design a nutrition plan for you with diet and supplements tailored to your specific needs.


Statins can contribute to nutritional deficiencies like CoQ10, Vitamin D and more, due to how they operate in the body. Deficiencies in these nutrients can lead to a range of diseases, and therefore if possible have your levels tested, check out the supplements above and book an appointment with me, so I can put you on a tailored plan to ensure you are making the right diet changes and taking the right amounts of supplements to optimize your health.

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